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一,Maitiro Akakosha Ekuita

1. Ropa Glucose Regulation

• Inokurudzira insulin secretion: Inomisikidza GLP-1 receptors pane pancreatic β-masero, inosimudzira kuburitswa kwe insulin kana shuga yeropa yakwira. Mhedzisiro yaro inodzikira kana mazinga eglucose akajairika, nekudaro achidzikisa njodzi ye hypoglycemia.

• Inoderedza kugadzirwa kweglucagon: Inoderedza hepatic gluconeogenesis, zvichiita kuti kuderedza kutsanya kweglucose yeropa.

• Inononoka kubuda mudumbu: Inoderedza chiyero chekudya chinopinda mudumbu diki, nokudaro kuderedza postprandial ropa glucose spikes.

2. Kudzora uremu

• Central appetite kudzvinyirirwa: Inoshanda pane hypothalamic satiety centre, inosimudzira satiety zviratidzo (semuenzaniso, activation yePOMC neurons) uye kuderedza nzara.

• Kuderedza kudya kwekudya: Kunonoka kubuda kwegastric uye kuchinjika kwezviratidzo zvedumbu kunowedzera kuderedza kudya.

3. Cardiovascular and Metabolic Protection

• Inovandudza lipid profile: Inoderedza triglyceride mazinga uye inowedzera high-density lipoprotein (HDL) cholesterol.

• Anti-atherosclerosis: Zvidzidzo zvemhuka zvinoratidza kuti inogona kudzvanya kuzvimba kwevascular plaque, kunyangwe iine mhedzisiro pamaplaque akamiswa.

• Cardiorenal kudzivirira: Miedzo mikuru yemakiriniki yakasimbisa kukwanisa kwayo kuderedza zviitiko zvemwoyo kune varwere vane chirwere cheshuga uye kunonoka kufambira mberi kwekushaya simba.