Fmoc-L-Lys[Eic(OtBu)-γ-Glu(OtBu)-AEEA-AEEA]-OH

Fmoc-L-Lys[Eic(OtBu)-γ-Glu(OtBu)-AEEA-AEEA]-OH

Fmoc-L-Lys[Eic(OtBu)-γ-Glu(OtBu)-AEEA-AEEA]-OH is functionalized amino acid building block yakagadzirirwa kuendeswa kwezvinodhaka uye bioconjugation. Iyo inoratidzira Eic (eicosanoid) moiety yekusangana kwelipid, γ-Glu yekunongedza, uye AEEA spacers yekuchinjika.

 
Tsvagiridzo & Zvishandiso:

Inoshandiswa muprodrug synthesis, ADC kuvandudza, uye nanocarrier dhizaini

Inovandudza membrane yakananga, kunyungudika, uye kugona kwekubatanidza

Inokodzera SPPS mune yepamusoro peptide-zvinodhaka conjugate research

Zvigadzirwa zvechigadzirwa (Gentolex Boka):

Fmoc-yakachengetedzwa, kuchena kwakanyanya (≥99%)

Iine mapoka eOtBu anogona kutsemuka ekugadzirisa synthesis

Fmoc-L-Lys[Eic(OtBu)-γ-Glu(OtBu)-AEEA-AEEA]-OH yakanakira kuburitsa masisitimu uye inoshanda peptide dhizaini.