Glepaglutide

Purogiramu inonzi Glepaglutide

Glepaglutide ndeyekureba-inobata GLP-2 analogi yakagadziridzwa kurapa pfupi bowel syndrome (SBS). Inowedzera kunyura kwemukati uye kukura, kubatsira varwere kuderedza kutsamira pane chikafu chevabereki.

Mechanism & Tsvagiridzo:

Glepaglutide inosungira kune glucagon-like peptide-2 receptor (GLP-2R) mumatumbo, ichikurudzira:
Mucosal kukura uye kuvandudzwa
Kuvandudzwa kwekudya kunovaka muviri uye kutorwa kwemvura
Yakaderedzwa intestinal kuzvimba

Zvidzidzo zvekiriniki zvakaratidza kuti Glepaglutide inogona kuwedzera intestinal basa uye kuvandudza hupenyu hwevarwere veSBS.

API Zvimiro (Gentolex Boka):

Yakareba-inoita peptide analog
Yakagadzirwa kuburikidza ne-soli-phase peptide synthesis (SPPS)
Kuchena kwepamusoro (≥99%), GMP-yakafanana nemhando

Glepaglutide API mushonga unovimbisa wekutadza kwematumbo uye kugadzirisa ura.