Canada Nguva 2022-01-25, Rhovac Pakutanga, kambani yakawana matare ane hukama neRV001 muUnited States, Europe neJapan. Iyi patent grant ichapa dziviriro yakakura yeRV001 mumisika mikuru uye kukwidzirisa zvipingamupinyi zvekambani.
Kufanana neiyo yakamboratidzwa Patent application, iyi Patent inovhara iyo RV001 cancer yekudzivirira uye zvakasiyana-siyana, pamwe nekushandiswa kwayo mukurapa / kudzivirira kwehongwe yegomarara. Pakati pavo, rhoc iri bundu-rakabatana antigen (taa) iro rinoyevedza mumhando dzakasiyana dzebunako. Akamborerwa, iyo Patent ichapera muna 2028-12 uye inotarisirwa kuwedzeredzwa pane kuwana gwaro rekuchengetedza dziviriro (CPSP).
01 Onilcamotide
Onilcamotide is a cancer maccine inosanganisira immunogenic mapeptides inotorwa kubva kuRASE MHURE Mhuri C (RHOL) Subcutaneous Administration of Onilcamotide inomutsa Immune System kuti Gymune sy lymphocyte (CTL) mhinduro kuRhoc masero ematehwe, saka kunyorera mabundu embato.
2020-11, RV001 yakapihwa yekupedzisira track dhizaini neFDA.
02 miedzo yekiriniki
Muna 2018, iyo chikamu chekiriniki yekiriniki yeimba yeimba yekubata kwekenza yeprostate yakatenderwa, uye varume vese makumi maviri nevaviri vakanyoreswa. Mhedzisiro yacho yakaratidza kuti Onilcamotide yaive yakachengeteka uye yakanyatsosheswa. Mukuwedzera, varwere vakagadzira mhinduro dzakasimba uye dzakasimba dzisingabvumirwe zvichitevera kurapwa. Muna 2021, kutevera kwezviitwa 19 zvezvidimbu izvi, makore matatu mushure mekupedza kurapwa naRhokapc . Pane awa, zvidzidzo gumi nematanhatu zvainge zvisina kana kuona PSA, uye zvitatu zvidzidzo zvakange zvanyatsononoka psa kufambira mberi. Psa ndeye protein yakagadzirwa neye prostate gland uye inoshandiswa kutevedzera kufambira mberi kwekanza yeprostate inozivikanwa.
Muna 2019, iyo RV001 Phase IIB Clinical Bravac (LIVEKWA, DOPOTOCOMS, Placebox Contred Cances Treste Cancer mushure mekuvhiyiwa / radiation. Iyi iib Clinical kutongwa International, multicenter yekudzidza nyaya mu 6 nyika dzeEurope (Denmark, Sweden, Belgium, Germany, neUnited Kingdom) neUnited States. Iyo yekuyedzwa yakazopera simba rekutengesa mu 2021-09, ine huwandu hwenzvimbo dzinosvika 175 dzakanyorwa, uye dzichapera muna 2022H1. Mukuwedzera, rhovac anoronga kuitisa preclinical ongororo inoongorora yakanangana nekupa chiratidzo chechiratidzo chekuwedzera kweRV001 mune zviratidzo.
Uyezve, komiti yekuchengetedza yekutarisa yakaitisa zvakare kuongorora kwekuchengetedza kweRV001 muna 2021-07, uye hapana zviitiko zvisingatarisirwi zvakawanikwa, izvo zvaienderana nechikamu chapfuura ini / 2 mhedzisiro.
Post Nguva: Kukadzi-17-2022