Orforglipron inyowani Type 2 chirwere cheshuga uye uremu kurapa mushonga uri kuvandudzwa uye inotarisirwa kuve imwe yemuromo kune zvinodhaka zvinobaya. Iyo ndeye glucagon-like peptide-1 (GLP-1) receptor agonist mhuri uye yakafanana neinowanzo shandiswa Wegovy (Semaglutide) uye Mounjaro (Tirzepatide). Iine mabasa ekugadzirisa shuga yeropa, kudzvinyirira kudya uye kuwedzera satiety, nokudaro kubatsira kudzora uremu uye mazinga ehuga.
Kusiyana nemishonga yakawanda yeGLP-1, iyo yakasarudzika mukana weOrforglipron iri mune yayo yemazuva ese yemuromo piritsi fomu kwete yevhiki kana yezuva jekiseni kutonga. Iyi nzira yekutonga yakawedzera zvakanyanya kutevedza kwevarwere uye nyore kushandisa, inomiririra kufambira mberi kwakakosha kune avo vasingafarire majekiseni kana kuti vanoramba majekiseni.
Mumiyedzo yekiriniki, Orforglipron yakaratidza yakanakisa kurasikirwa uremu mhedzisiro. Dhata inoratidza kuti vatori vechikamu vakatora Orforglipron zuva nezuva kwemavhiki makumi maviri nematanhatu akateedzana vakawana avhareji yekurasikirwa kwe8% kusvika 12%, zvichiratidza kushanda kwayo kwakakosha mukudzora uremu. Mhedzisiro iyi yakaita kuti Orforglipron ive tariro nyowani yeramangwana kurapwa kwerudzi rwechipiri chirwere cheshuga uye kufutisa, uye zvakare inoratidza maitiro akakosha mumunda weGLP-1 mishonga, iyo iri kusimuka kubva kune jekiseni kuenda kumuromo dosage mafomu.
Nguva yekutumira: Jul-07-2025