Pregabalin yekurapa kwePeripheral Neuralgia uye kurapwa kwekutambisa kweparutivi rweparutivi

Pharmacological mhedzisiro
Pregabalin ane yakanaka yekurapa maitiro pane epilipsy. Zvidzidzo zveMhuka Dzakawanda Dzemhuka Dzemhando dzeKubhadhara Models dzakaratidza kuti Pregabalin anogona kudzivirira kubatwa nepileptic kubatwa, uye dofo rayo rinoshanda nderimwe katatu kuderera pane gabipentin. Zvidzidzo zvakawana kuti pregabalin anogona kuderedza sensory uye motor cord cord Spinal Stimuli. maitiro a. Zvidzidzo zvemhuka zvakawana kuti pregabalin inogona kunge iine zvakanakira musanganiswa ne opioids. Pregabalin inopa sarudzo nyowani yekubatwa kwekiriniki yekurwadzisa neuropathic kurwadziwa.

Michina
Pregabalin inogona kuderedza iyo calcium kuburitswa kweimwe neurotransmitters nekufambisa calcium crantel basa. Kunyangwe pregabalin chivakwa cherudzi rweInhtbitory neurotransmitter uropi hwemakonzo, uye hauna maitiro anorwara paGaba anokwidza kana kusvibiswa. Nekudaro, chidzidzo chakawana kuti kuratidzwa kwenguva refu kwetsika yetsika kune pregabalin yakawedzera density yegadheni yeGaba vatakuri uye huwandu hwekushanda gaba rekufambisa. Pregabalin haivharidze sodium nzira, haana basa pane opioid Receptes, haina basa rekutengesa kuDopmine uye Serotonin Receverivation, uye haitongi kuongororwa kweDopmine, Serotonin, kana Norepinephrine. ingest.

Kurongeka kwekudyidzana
1. Izvo hazvisi metabolized neiyo cytochrome P450 System, saka, hazviwanzoita zvimwe zvinodhaka. Hazvibatanidze zvePharmacokinetics of Aniepilepic zvinodhaka (senge sodium caprocet, phenytoin, maroti, phenobarbital, otheti yekudzivirira, omarara hypoglycemic vamiriri, diurtics, uye insulin.
2. Kana ichi chigadzirwa chishandiswa pamwe neOxycodone, basa rayo rekuziva richadzikiswa uye rekukuvara kwemotokari kukuvadzwa kuchavandudzwa.
3. Iyo ine inowedzera mhedzisiro neLorazepam uye Ethanol.