Products
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Givosiran
Givosiran API is a synthetic small interfering RNA (siRNA) yakadzidzira kurapwa kweacute hepatic porphyria (AHP). Inonyanya kunanga iyoALAS1gene (aminolevulinic acid synthase 1), iyo inobatanidzwa muheme biosynthesis nzira. Vatsvakurudzi vanoshandisa Givosiran kuongorora RNA interference (RNAi) -based therapies, chiropa-chinonangwa gene kunyarara, uye modulation ye metabolic nzira dzinobatanidzwa mu porphyria uye ane hukama hwemajini kusagadzikana.
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Pegcetacoplan
Pegcetacoplan inonzi pegylated cyclic peptide inoshanda seyakanangwa C3 complement inhibitor, yakagadzirirwa kurapwa kwezvirwere zvinopindirana zvakadai separoxysmal nocturnal hemoglobinuria (PNH) uye geographic atrophy (GA) muzera remacular degeneration.
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Plozasiran
Plozasiran API is a synthetic diki inopindira RNA (siRNA) yakagadzirirwa kurapwa kwe hypertriglyceridemia uye ine hukama hwemoyo uye metabolic kusagadzikana. Inonangana neAPOC3gene, iyo inokodha apolipoprotein C-III, mutongi akakosha we triglyceride metabolism. Mukutsvagisa, Plozasiran inoshandiswa kudzidza RNAi-based lipid-kudzikisa marongero, gene-kunyarara, uye kwenguva refu-kuita marapirwo emamiriro ezvinhu akadai semhuri chylomicronemia syndrome (FCS) uye yakasanganiswa dyslipidemia.
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Zilebesiran
Zilebesiran API ndeyekuferefeta diki inopindira RNA (siRNA) yakagadzirirwa kurapwa kwehypertension. Inonangana neAGTgene, iro rinoisa angiotensinogen - chikamu chakakosha che renin-angiotensin-aldosterone system (RAAS). Mukutsvaga, Zilebesiran inoshandiswa kudzidza nzira dzekunyarara kwemajini kwenguva refu yekudzivirira kweropa, RNAi kuburitsa matekinoroji, uye basa rakakura reiyo RAAS nzira muzvirwere zvemoyo uye renal.
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Palopegteriparatide
Palopegteriparatide inguva yakareba inobata parathyroid hormone receptor agonist (PTH1R agonist), yakagadzirirwa kurapwa kwekusingaperi hypoparathyroidism. Iyo pegylated analog yePTH (1-34) yakagadzirirwa kupa yakagadzikana karusiyamu mutemo nekamwe-vhiki dosing.
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GHRP-6
GHRP-6 (Kukura kweHormone Kuburitsa Peptide-6) ndeye synthetic hexapeptide inoshanda sekukura kwehomoni secretagogue, ichikurudzira kuburitswa kwemuviri kwekukura kwehomoni (GH) nekuita iyo GHSR-1a receptor.
API Features:
Kuchena ≥99%
Yakagadzirwa kuburikidza ne-soli-phase peptide synthesis (SPPS)
Inopihwa R&D uye kushandiswa kwekutengesa
GHRP-6 inyanzvi yekutsvagisa peptide yerutsigiro rwemetabolism, kuvandudzwa kwemhasuru, uye hormonal modulation.
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GHRP-2
GHRP-2 (Kukura kweHormone Kuburitsa Peptide-2) ndeyekugadzira hexapeptide uye ine simba kukura hormone secretagogue, yakagadzirirwa kukurudzira kuburitswa kwechisikigo kwekukura kwehomoni (GH) nekuita iyo GHSR-1a receptor mu hypothalamus uye pituitary.
API Zvimiro:
Kuchena ≥99%
Inowanikwa kuR&D uye kushambadzira kwekutengesa, ine yakazara QC zvinyorwa
GHRP-2 inokosha tsvakurudzo peptide muminda endocrinology, regenerative mushonga, uye zera-ane kurapa.
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Hexarelin
Hexarelin is a synthetic growth hormone secretagogue peptide (GHS) uye ine simba GHSR-1a agonist, yakagadziridzwa kukurudzira endogenous kukura kwehomoni (GH) kusunungurwa. Ndeyemhuri yeghrelin mimetic uye inoumbwa neamino acids matanhatu (hexapeptide), inopa kugadzikana kwemetabolism uye yakasimba GH-kuburitsa mhedzisiro kana ichienzaniswa nekare analogs seGHRP-6.
API Features:
Kuchena ≥ 99%
Yakagadzirwa kuburikidza ne-soli-phase peptide synthesis (SPPS)
GMP-yakafanana zviyero, yakaderera endotoxin uye zvinonyungudutsa zvinosara
Flexible supply: R&D kune yekutengeserana chiyero
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Melanotan II
API Zvimiro:
Kuchena kwepamusoro ≥ 99%
Yakagadzirwa kuburikidza nechakasimba-chikamu peptide synthesis (SPPS)
Yakaderera endotoxin, yakaderera yakasara zvinonyungudutsa
Inowanikwa muR&D kusvika pachiyero chekutengesa -
Melanotan 1
Melanotan 1 API inogadzirwa uchishandisa yakasimba chikamu peptide synthesis (SPPS) tekinoroji pasi peGMP-semhando yekudzora mamiriro.
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Kuchena kwepamusoro ≥99%
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Solid-phase peptide synthesis (SPPS)
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GMP-kufanana nekugadzira zviyero
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Zvinyorwa zvizere: COA, MSDS, data yakagadzikana
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Scalable supply: R&D kune nhanho dzekutengesa
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MOTS-C
MOTS-C API inogadzirwa pasi pemamiriro akasimba eGMP-akafanana nekushandisa solid phase peptide synthesis (SPPS) tekinoroji kuve nechokwadi chemhando yepamusoro, kuchena kwepamusoro uye kugadzikana kwepamusoro kwekutsvaga uye kushandiswa kwekurapa.
Product Features:Kuchena ≥ 99% (yakasimbiswa neHPLC uye LC-MS),
Yakaderera endotoxin uye yakasara solvent yemukati,
Yakagadzirwa zvinoenderana neICH Q7 uye GMP-senge maprotocol,
Inogona kuwana kugadzirwa kwakakura, kubva pamilligram-level R&D batches kusvika giramu-level uye kilogram-level yekutengesa kushambadzira. -
Ipamorelin
Ipamorelin API inogadzirirwa nepamusoro-standard ** solid phase peptide synthesis process (SPPS) ** uye inopinda kucheneswa kwakasimba uye kuongororwa kwehutano, yakakodzera kushandiswa kwepombi yekutanga mukutsvakurudza kwesayenzi nekusimudzira uye makambani emishonga.
Zvigadzirwa zvechigadzirwa zvinosanganisira:
Kuchena ≥99% (HPLC bvunzo)
Hapana endotoxin, yakaderera yakasara solvent, yakaderera simbi ion kusvibiswa
Ipa iyo yakazara seti yemhando magwaro: COA, kugadzikana chidzidzo chirevo, kusachena spectrum ongororo, nezvimwe.
Customizable gram-level ~ kilogram-level supply