REVERSE T3 yeprotein synthesis, thermoregulation, kugadzirwa kwesimba uye mutemo
Product Detail
| Zita | REVERSE T3 |
| CAS nhamba | 5817-39-0 |
| Molecular formula | C15H12I3NO4 |
| Molecular uremu | 650.97 |
| Melting point | 234-238°C |
| Boiling point | 534.6±50.0°C |
| Kuchena | 98% |
| Storage | Ramba munzvimbo ine rima, Yakavharwa pakaoma, Chengetedza mufiriza, pasi -20°C |
| Form | Upfu |
| Color | Pale Beige kuna Brown |
| Packing | PE bag+Aluminium bag |
Mashoko anoreva zvakafanana
ReverseT3(3,3',5'-Triiodo-L-Thyronine);L-Tyrosine,O-(4-hydroxy-3,5-diiodophenyl)-3-iodo-;(2S) -2-aMino-3-[4-(4-hydroxy-3,5-diiodophe) noxy)-3-iodophenyl]propanoicacid;REVERSET3;T3;LIOTHYRONIN;L-3,3',5'-TRIIODOTHYRONINE;3,3′,5′-Triiodo-L-thyronine(ReverseT3) mhinduro
Pharmacological Effect
Tsanangudzo
Iyo thyroid gland ndiyo hombe endocrine gland mumuviri wemunhu, uye zvinhu zvikuru zvinoshanda zvakavanzwa ndeye tetraiodothyronine (T4) uye triiodothyronine (T3), iyo yakakosha zvakanyanya kune mapuroteni synthesis, mutemo wekushisa kwemuviri, kugadzirwa kwesimba uye basa rekutonga. Yakawanda yeT3 iri muserum inoshandurwa kubva kune peripheral tissue deiodination, uye chikamu chiduku cheT3 chakanyatsovharwa nehutachiona uye chinobudiswa muropa. Yakawanda yeT3 muserum inosungirwa kusunga mapuroteni, angangoita 90% ayo anosungirirwa ku thyroxine-binding globulin (TBG), imwe yasara inosungirwa kualbumin, uye shoma shoma inosungirirwa ku thyroxine-binding prealbumin (TBPA). Zviri muT3 muserum ndeye 1/80-1/50 yeT4, asi biological chiitiko cheT3 ndeye 5-10 nguva yeT4. T3 inoita basa rakakosha pakutonga chimiro chemuviri wemunhu, saka zvakakosha zvikuru kuona iyo T3 yemukati serum.
Clinical Kukosha
Kutsunga kwe triiodothyronine chimwe chezviratidzo zvinonzwisisika zvekuongororwa kwe hyperthyroidism. Kana hyperthyroidism ichiwedzera, zvakare inotangira kudzoka kwe hyperthyroidism. Mukuwedzera, ichawedzerawo panguva yekuzvitakura uye acute hepatitis. Hypothyroidism, nyore goiter, acute uye chisingaperi nephritis, chisingaperi hepatitis, chiropa cirrhosis yakaderera. Serum T3 concentration inotaridza mashandiro ethyroid gland pamatishu akapoteredzwa pane kuita secretory state yethyroid gland. T3 kutsunga inogona kushandiswa kuongororwa kweT3-hyperthyroidism, kuzivikanwa kwekutanga hyperthyroidism uye kuongororwa kwepseudothyrotoxicosis. Iyo yese serum T3 level inowanzoenderana nekuchinja kweT4 level. Icho chiratidzo chinonzwisisika chekuongororwa kwehutano hwehutachiona, kunyanya kuongororwa kwekutanga. Icho chiratidzo chakananga chekuongorora cheT3 hyperthyroidism, asi haina kukosha kwekuongororwa kwehutachiona hwehutachiona. Kune varwere vanobatwa nemishonga yethyroid, inofanira kusanganiswa ne thyroxine yose (TT4) uye, kana zvichidiwa, thyrotropin (TSH) panguva imwe chete kuti ibatsire kutonga hutachiona hwehutachiona.
