RU-58841 Inoshandiswa Sekudzivirira Kurasika Kwebvudzi uye Kusvibiswa Kwevarume
Product Detail
| Zita | RU-58841 |
| CAS nhamba | 154992-24-2 |
| Molecular formula | C17H18F3N3O3 |
| Molecular uremu | 369.34 |
| Nhamba yeEINECS | 1592732-453-0 |
| Boiling Point | 493.6±55.0 °C(Zvakafanotaurwa) |
| Density | 1.39 |
| Kuchengetedza mamiriro | Yakavharwa pakaoma,Chengeta mufiriji, pasi pe -20°C |
| Form | Upfu |
| Color | Chena |
| Packing | PE bag+Aluminium bag |
Mashoko anoreva zvakafanana
RU58841. onnitrile;4--[3-(4-Hydroxybutyl)-4,4-diMethyl-2,5-dioxoiMidazolidin-1-yl]-2-(trifluoroMethyl) ben zonitrile;RU-58841E:candyli(at)speedgainpharma(dot)com;CS-637;RU588841;RU58841;RU58841;RU-58841
Pharmacological Effect
Tsanangudzo
RU 58841 (PSK-3841) inonzi androgen receptor antagonist inokurudzira kukura kwebvudzi.RU58841 mushonga wekuferefeta wakagadzirwa kuti urapwe kurwisa androgenic alopecia, inozivikanwawo semurume pateni mhanza(MPD).
Seye-topical anti-androgen, nheyo yayo yekuita haina kufanana neyefinasteride. Finasteride inoshanda zvakananga pa 5α reductase, inhibisa kutendeuka kwe testosterone muDHT, uye inoderedza zvinyorwa zveDHT mumuviri. RU58841 inovhara kusangana pakati pe dihydrotestosterone uye vhudzi follicle receptors, haisi kuderedza zvakananga DHT zvinyorwa, asi inoderedza kusungwa kweDHT uye bvudzi follicle receptors, kuitira kuti uwane chinangwa chekurapa androgenetic alopecia.
4--[3- (4-Hydroxybutyl) -4,4-dimethyl-2,5-dioxo-1-imidazolidinyl] -2- (trifluoromethyl) benzonitrile inogona kushandiswa semushonga Chemical synthesis intermediates.Kana 4--[3-(4-hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazolidinyl] -2-(trifluoromethyl)benzonitrile yakafemerwa, Fambisa murwere kumhepo itsva;Muchiitiko chekubata kweganda, bvisa zvipfeko zvakasvibiswa, geza ganda zvakakwana nesipo nemvura, uye tsvaga kurapwa kana kusagadzikana kukaitika;
Side Effect
RU58841 inoshandiswa kune scalp, inobatwa nevhudzi rebvudzi, uye inotaura, inogona kupinda muropa uye inokanganisa dzimwe nhengo dzomuviri. Asi hapana systemic mativi emhedzisiro akawanikwa mune zvidzidzo zvetopical application mutsoko. Zvisinei, vamwe vanhu vakaedza RU58841 vanoti vakawana zvimwe zvinogona kuitika kubva pakushandisa RU, kusanganisira ganda rinopisa, kuderera kwe libido, erectile dysfunction, kusvotwa, maziso matsvuku, dzungu, uye musoro.
