Boc-His(Trt)-Aib-Gln(Trt)-Gly-OH

Boc-His(Trt)-Aib-Gln(Trt)-Gly-OH

Tsvagiridzo Yekushandisa:
Iyi tetrapeptide yakachengetedzwa inoshandiswa mu peptide synthesis uye conformational zvidzidzo. Iko kubatanidzwa kweAib (α-aminoisobutyric acid) inobvumira vaongorori kuti vaongorore helical zvimiro uye kupeta maitiro mumapfupi peptides. Iwo akachengetedzwa anoshanda mapoka (Boc, Trt) anovimbisa kugadzikana uye kusarudzwa panguva yakasimba-chikamu peptide synthesis, ichiita iyo yakakosha modhi yekudzidza peptide musana dynamics uye parutivi-cheni kudyidzana.

Basa:
Boc-His(Trt)-Aib-Gln(Trt)-Gly-OH inoshanda semuenzaniso wekomisheni yekuongorora kugadzikana kwepeptide uye structural motifs. Aib inobatsira mukudzikamisa helical, nepo histidine uye glutamine zvisaririra zvinopa nzvimbo dzekudyidzana, dzinobatsira mukugadzira bioactive peptides kana kutevedzera mapuroteni zvimedu. Inogona zvakare kuve inotangira peptides inoshanda mukuvandudza zvinodhaka kana biochemical assays.