Daptomycin 103060-53-3 Zvirwere zvinotapukira
Chigadzirwa Chinhu
| Zita | Daptomycin |
| Nhamba | 103060-53-3 |
| Molecular Formula | C72H101n17o26 |
| Sreek inoremerwa | 1620.67 |
| Einecs nhamba | 600-389-2 |
| Inonyungudika | 202-204 ° C |
| Boiling Point | 2078.2 × 65.0 ° C (yakafanotaura) |
| Density | 1.45 ± 0.1 g / cm3 (yakafanotaurwa) |
| Flash Pfungwa | 87 ℃ |
| Mamiriro ekuchengetedza | Chisimbiso mune chakaoma, chengetedza mu freezer, pasi pe -20 ° C |
| Solubility | Methanol: soluble5mg / ml |
| Acidity coefficient | (pka) 4.00 ± 0.10 (yakafungidzira) |
| Fomu | poda |
| Ruvara | isina ruvara kuti ifadze yero |
Synonyms
N- [n- (1-quedecycy) -l-trp-d-asn-l-lec-l-fan - - () - ; N- [n-decichayl-l-trp-d-asn-l-asp-l-fan - Ecyl) -l-Tryptophyl-D-L-α-ASPartyl-l-ot-aspartylglycycyl-d-seryl- (3r)-3-methyl-l-α- Glutamyl-α, 2-diamino-γ-oxo-benzenebutanoicicid (13-4) Lactone
Tsananguro
Iyo Antibiotic Daptomycin Lipopeptide Antbiotic neChimiro chitsva chakabviswa kubva kuBellown Cell Cell Cell Cell PeillyCan Kuchinja zvivakwa zveCytoplasmic membrane inogona kukanganisa mabheti ehutachiona membrane basa munzira dzakawanda uye nekukurumidza kuuraya hutachiona hwakanaka-gramu. Pamusoro pekugona kwayo kuita zvechirwere chakanyanya kukodzera giredhi, Daptomycin yakanyanya kukosha kune miganho yekuzvisarudzira yakaratidza kuti methcillin, Vancomycin, uye LineZodid mu vitro. Iyo ine chiitiko chine simba, uye ichi chivakwa chine zvakakosha zvechiriviri zvakakanganisika kune varwere vanorwara zvisina hutachiona. EOSinophilic PNEUMONIA chirwere chisingawanzo uye chakakura kwazvo nezviratidzo zvinosanganisira fivha, kukosora, kupfupika kwekufema, uye kunetseka kufema.
Antibacterial mhedzisiro
DAPTOMYCE ine yakanaka bactiosostathi chiitiko kurwisa akasiyana-siyana mabhakitiriya, akadai se mic = 0.06-0 Mic = 0.0625 ~ 1μg / ml yeBaceria, Mic = 0,13 ~ 0.5 mp3. uye mic ye enterococccus inopesana ne glycopeptide mishonga inorwisa mabhakitiriya ndeye 1 ~ 2μg / ml.
