Leuprorelin acetate inogadzirisa secretion yeGonadal Mahormone
Chigadzirwa Chinhu
| Zita | Leuprorelin |
| Nhamba | 53414-56-0 |
| Molecular Formula | C59H84n1212 |
| Sreek inoremerwa | 1209.4 |
| Einecs nhamba | 633-395-9 |
| Kutenderera chaiko | D25 -31.7 ° (c = 1 mu1% acetic acid) |
| Density | 1.44 ± 0.1 g / cm3 (yakafanotaura) |
| Kuchengetedza mamiriro | -15 ° C |
| Fomu | Neat |
| Acidity coefficient | (pka) 9.82 ← 0.15 (yakafanotaura) |
| Solubility yemvura | Nyura mumvura pa 1mg / ml |
Synonyms
LH-RHLEUPLIDE; LUPLIDELE; LUPLIDELID (HOME); -Nhet9) -lutehinizinghormone-kusunungura Herformone;
Pharmacological mhedzisiro
Leuplaride, Goserelin, Trarelin mishonga yakati wandei inowanzoshandiswa mumakiriniki ekubvisa ipoko yekurapa kenza yemazamu emazamu uye cancer. . Ndokunge, iyo Gonadotropin yakavanzika neiyo pitlu inoderera, iyo inotungamira kuderera kwakakosha muhofisi yehofisi yakavhenekerwa neovary.
Leupldide is a gonadotropin-kuburitsa hormone (GNRH) Analog, yakaumbwa september ye9 amino acids. Chigadzirwa ichi chinogona kukanganisa basa rekushanda-pruadal system, kupokana kune protenty Iyo ine zvakare ine yakasimba inhibitory yekukanganisa pane pituitary-gonad basa pane gnrh. Muchikamu chekutanga chekurapa, follicle inomutsa hormone (FSH), LH, Estrogen Ingovererwa kwenguva pfupi yeiyo Gshland Gland, LH uye Estrogen Inhibund, inokonzerwa nekuvimba nehomwe dzehomwe dzepabonde. Zvirwere zvebonde (zvakadai sekanza yeprostate, encometriosis, etc.) vane maitiro ekurapa.
Parizvino, iyo acetate yemunyu inoshandiswa kunyanya kushandiswa kiriniki, nekuti kuita kweiyo leupleide acetate yakanyanya kugadzikana pamhepo tembiricha. Mvura inofanira kuraswa. Inogona kushandiswa kurapwa kwezvinodhaka kwekupedza uye uterine fibrari Inogona zvakare kushandiswa semubhadharo usati watorwa, izvo zvinogona kutetepa iyo endometrium, kuderedza Edema, uye kuderedza kuoma kwekuvhiyiwa.
