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Liraglutide Anti-Diabetics yeRopa Shuga Kudzora Cas No.204656-20-2

Tsananguro pfupi:

Inoshanda Ingirient:Liraglutide (Analog of Human Glucagon-Senge Peptide-1 (GLP-1) Yakagadzirwa neJast In Kuburikidza neGenetic Tekinoroji).

CHEMICAL ZITA:Arg34lys26- (n-and-(γ-glu (n-n-α-hexadecanoyl)) - GLP-1 [7-37]

Zvimwe zvinoshandiswa:Disodum Hydrogen Dhihydrate, Propyrochloric Acid uye / kana Sodium Hydroxide (seP Shandura chete), phenol, uye mvura ye jekiseni.


Chigadzirwa Chinhu

Zvigadzirwa tags

Chigadzirwa Chinhu

CAS 204656-20-25 Molecular Formula C172H265N43O51
Sreek inoremerwa 3751.20 Chitarisiko Chena
Kuchengetedza mamiriro Chiedza Chekurwisa, 2-8 degree Package Aluminium foil bag / vial
Kuchena ≥98% Zvekufambisa Carmar Carmand uye inotonhorera yekuchengetedza kuburitsa

Zvinongedzo zve liragludide

Liraglutide

Inoshanda Ingirient:

Liraglutide (Analog of Human Glucagon-Senge Peptide-1 (GLP-1) Yakagadzirwa neJast In Kuburikidza neGenetic Tekinoroji).

CHEMICAL ZITA:

Arg34lys26- (n-and-(γ-glu (n-n-α-hexadecanoyl)) - GLP-1 [7-37]

Zvimwe zvinoshandiswa:

Disodum Hydrogen Dhihydrate, Propyrochloric Acid uye / kana Sodium Hydroxide (seP Shandura chete), phenol, uye mvura ye jekiseni.

Application

Type 2 chirwere cheshuga

Liraglutide inovandudza kudzora kweropa glucose. Iyo inoderedza hyperglycemia yakanangana neawa (kwemaawa makumi maviri nemana mushure mekutonga
Izvo zvakakodzera kune varwere vane shuga yeropa ichiri kudzorwa mushure mekunge yakakwirisa iyo yekudzikiswa dofo ye metformin kana sulfonylureas chete. Iyo inoshandiswa mukubatanidzwa ne metformin kana sulfonylureas.
Zvinoita nenzira inochengetedzwa-siyana, zvichireva kuti inomutsa chinyoronyoro insulin kana huwandu hweropa hwakakwira kupfuura zvakajairwa, zvichidzivirira "overshoot". Nekuda kweizvozvo, zvinoratidza njodzi isina hanya ye hypoglycemia.
Iyo ine mukana wekusindimira apoptosis uye inomutsa kuumbwa kwe beta masero (anoonekwa muzvidzidzo zvemhuka).
Iyo inoderedza kudya uye inhibits muviri uremu kuwana, sezvakaratidzwa mumusoro-kune-musoro wekudzidza kupesana neyekuchiva.

Pharmacological chiito

Liraglutide ndeye GLP-1 Analog ne 97% Sequence Homology kuGlp-1, iyo inogona kusunga uye kumisa iyo GLP-1 Receptor. Iyo GLP-1 Receptor ndiyo Yakatarwa GLP-1, iyo Endogenus Incretin Hormone iyo inosimudzira Glucentions-Insulin Secretin Symbol of Pancreatic ce Services. Kusiyana neNative GLP-1, iyo pharmacokinetic uye pharmacodynamic profiles yeLiragludide muvanhu yakakodzera kamwe-zuva nezuva dosing recing. Mushure mekukura kwepasirese, maitiro ayo ekuita kwenguva refu anosanganisira: kuzvibata-kushamwaridzana kunotora mvura; kusunga kune albiniki; Yakakwirira enzyme kugadzikana uye saka kureba plasma hafu-hupenyu.

Chiitiko cheLiragludide inodururwa neyakajairwa neyekutaurirana neGLP-1 Receptor, zvichikonzera kuwedzera kweCyclic adenosine monophatehate (Musasa). Liraglutide inomutsa chinyoronyoro insulin muchikamu cheGlucenti

Naizvozvo, apo glucose yeropa, insulin yakavanzika inokurudzirwa, nepo segrigonion yegrogonion ichidzimwa. Mukupesana, Liraglutide inoderedza chinyoronyoro insulin panguva hypoglycemia pasina kukanganisa chigaro cheGlucaggon. Iyo hypoglycemic michina ye liragldide zvakare inosanganisira kusagadzikana zvishoma kweGastric kusundira nguva. Liraglutide inoderedza muviri uremu uye muviri wemuviri nekudzora nzara uye simba kudya.


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