Palopegteriparatide

Purogiramu inonzi Palopegteriparatide

Palopegteriparatide inguva yakareba inobata parathyroid hormone receptor agonist (PTH1R agonist), yakagadzirirwa kurapwa kwekusingaperi hypoparathyroidism. Iyo pegylated analog yePTH (1-34) yakagadzirirwa kupa yakagadzikana karusiyamu mutemo nekamwe-vhiki dosing.

Mechanism & Tsvagiridzo:
Palopegteriparatide inosunga kuPTH1 receptors, kudzorera calcium uye phosphate balance ne:

• Kuwedzera serum calcium

• Kuderedza weti calcium excretion

• Kutsigirabone metabolism uye mineral homeostasis