Atosiban Acetate Inoshandiswa kune Anti Premature Birth
Product Detail
| Zita | Atosiban |
| CAS nhamba | 90779-69-4 |
| Molecular formula | C43H67N11O12S2 |
| Molecular uremu | 994.19 |
| Nhamba yeEINECS | 806-815-5 |
| Boiling point | 1469.0±65.0 °C (Zvakafanotaurwa) |
| Density | 1.254±0.06 g/cm3(Zvakafanotaurwa) |
| Kuchengetedza mamiriro | -20°C |
| Solubility | H2O:≤100 mg/mL |
Tsanangudzo
Atosiban acetate is disulfide-bonded cyclic polypeptide ine 9 amino acids.Imodified oxytocin molecule panzvimbo 1, 2, 4 uye 8. N-terminus ye peptide is 3-mercaptopropionic acid (thiol uye The sulfhydryl boka re [Cys] 6 rinoumba disulfide bond), C-terminal ndiyo muchimiro cheamide, yechipiri amino acid paN-terminal is ethylated modified [D-Tyr(Et)]2, uye atosiban acetate inoshandiswa mumishonga sevhiniga Inowanikwa muchimiro cheasidhi munyu, kazhinji. inozivikanwa seatosiban acetate.
Application
Atosiban is oxytocin uye vasopressin V1A yakasanganiswa receptor antagonist, iyo oxytocin receptor yakafanana neiyo vasopressin V1A receptor.Kana iyo oxytocin receptor yakavharwa, oxytocin inogona kuramba ichiita kuburikidza neV1A receptor, saka zvakakosha kuvhara nzira mbiri dziri pamusoro apa panguva imwe chete, uye kupesana kumwe chete kwechigadziro chimwe chete kunogona kuvhiringidza kukanganiswa kwechibereko.Ichi zvakare chimwe chezvikonzero zvikuru nei β-receptor agonists, calcium channel blockers uye prostaglandin synthase inhibitors isingakwanise kuvharisa uterine contractions.
Mhedzisiro
Atosiban inobatanidza receptor antagonist ye oxytocin uye vasopressin V1A, chimiro chayo chemakemikari chakafanana nezviviri, uye ine hukama hwepamusoro hwema receptors, uye inokwikwidzana neoxytocin uye vasopressin V1A receptors, nokudaro ichivhara nzira yekuita ye oxytocin uye vasopressin uye kuderedza. uterine contractions.
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