Elamipretide

Purogiramu inonzi Elamipretide

Elamipretide inonzi mitochondria-targeted tetrapeptide yakagadzirwa kurapa zvirwere zvinokonzerwa nekusashanda kwemitochondrial, kusanganisira primary mitochondrial myopathy, Barth syndrome, uye kukundikana kwemoyo.

Mechanism & Tsvagiridzo:
Elamipretide inosarudza cardiolipin mukati memitochondrial membrane, ichivandudza:
Mitochondrial bioenergetics
Kugadzirwa kweATP
Kufema kweserura uye kushanda kwenhengo

Yakaratidza kugona kudzoreredza chimiro chemitochondrial, kuderedza oxidative kusagadzikana, uye kugadzirisa tsandanyama uye kushanda kwemoyo mune zvese zvekiriniki uye preclinical zvidzidzo.