Hexarelin

Hexarelin API - Chigadzirwa Overview

Hexarelinis a synthetickukura kwehomoni secretagogue peptide (GHS)uye zvine simbaGHSR-1a agonist, yakagadzirwa kuti ikurudzireendogenous kukura hormone (GH) kusunungurwa. Ndezvaghrelin mimetic mhuriuye inoumbwa neamino acids matanhatu (hexapeptide), inopa kugadzikana kwemetabolism uye yakasimba GH-kuburitsa mhedzisiro kana ichienzaniswa neyekare analogs seGHRP-6.

Hexarelin inodzidzwa zvakanyanya kune yayo mashandisirwo mukatiendocrinology, kutambisa tsandanyama, kugadzirisa mwoyo, uye anti-kuchembera kurapa, nekuda kwekugona kwayo kusimudza GH uyeinsulin-yakafanana nekukura chinhu 1 (IGF-1)mazinga pasina kuunza zvakananga mahormone ekunze.

Nzira Yekuita

Hexarelin inosunga kune iyokukura kwehomoni secretagogue receptor (GHSR-1a)pane pituitary uye hypothalamus, kutevedzera chiito cheghrelin- nzara yepanyama yemuviri uye GH-inoburitsa mahormone.

Zviito zvakakosha zvemuviri:

• Inokurudzira pulsatile GH kusunungurwa

• Inowedzera kutendereraIGF-1mazinga

• Anosimudziraanabolic mhedzisiro(kukura kwetsandanyama, kupora)

• Inotsigiramafuta metabolismuyekuvandudzwa kwesero

• May kuratidzacardioprotectiveuyeanti-apoptoticmigumisiro

Kusiyana nemamwe mapeptide eGHS, Hexarelin anoitakwete zvakanyanya kuwedzera cortisol kana prolactin, inopa yakachena endocrine mbiri.

Tsvagiridzo uye Kurapa Kunogona

1. Kukura Kwetsandanyama & Kudzoreredza

• Anosimudzirakuonda kwemuviridevelopment

• Inosimudzirakugadzirisa kwemhasuru uye kuvandudzwa

• Akadzidza mukatisarcopenia, cachexia, uye kupora mushure mekuvhiyiwa

2. Cardiovascular Protection

• Preclinical zvidzidzo zvinoratidzakuvandudza kushanda kwemwoyomushure mekukuvara kwemyocardial

• Zvinoderedzacardiac fibrosisuye inowedzerakuruboshwe ventricular ejection chikamu

• Zvinogona kushandiswa mukukundikana kwemoyouyekuchembera kwemwoyomienzaniso

3. Mafuta Metabolism & Anti-Kukwegura

• Inowedzeralipolysisuye inovandudzainsulin sensitivity

• Inotsigiraanti-aging therapieskuburikidza neGH/IGF-1 axis stimulation

• Inogona kubatsira kuchengetedzakuwanda kwemapfupa uye hutano hwekubatana

API Zvimiro (Gentolex Boka)

• Kuchena ≥ 99%

• Yakagadzirwa kuburikidzasolid-phase peptide synthesis (SPPS)

• GMP-yakafanana zviyero, yakaderera endotoxin uye zvinonyungudutsa zvinosara

• Flexible supply:R&D kune chiyero chekutengeserana