Pulegone

Pulegone API

Pulegone (molecular formula: C₁₀H₁₆O) is monoterpene ketone compound inotorwa kubva kune yakasikwa chirimwa mafuta anokosha, ayo anowanikwa zvakanyanya mumint (Mentha), verbena (Verbena) uye zvirimwa zvine hukama. Sechinhu chechisikigo chine kunhuhwirira uye yakakwira biological chiitiko, Pulegone akagamuchira kutariswa kwakawanda muminda yemishonga yechisikigo, botanical pesticides, anoshanda emazuva ese makemikari uye mishonga mbishi zvinhu mumakore achangopfuura.

Iyo Pulegone API yatinopa ndeye yakakwirira-kuchena komisheni inowanikwa kuburikidza nekunyatso kupatsanurwa uye kucheneswa maitiro, ayo anosangana nemhando yemhando yemishonga kana maindasitiri mamakisi uye inokodzera kwakasiyana kushandiswa sekutsvagisa kwesainzi nekusimudzira uye yepakati synthesis.

Tsvagiridzo kumashure uye pharmacological mhedzisiro

1. Anti-inflammatory effect

Nhamba huru yemhuka uye masero ekuongorora zvidzidzo zvakaona kuti Pulegone inogona kudzivisa kusunungurwa kwezvinhu zvinoputika (zvakadai seTNF-α, IL-1β uye IL-6), inogadzirisa COX-2 uye NF-κB nzira dzechiratidzo, uye nokudaro kuratidza hukuru hunopesana nehutachiona hunogona kuitika mumhando dzezvirwere zvakadai se rheumatoid arthritis uye kuputika kweganda.
2. Analgesic uye sedative migumisiro

Pulegone ine imwe inhibitory mhedzisiro pane yepakati tsinga system uye inoratidza pachena analgesic mhedzisiro mumhando dzemhuka. Nzira yaro inogona kunge yakabatana nekugadzirisa kweGABA neurotransmitter system. Iine mukana wekushandiswa seadjuvant kurapa kwekunetseka kwakanyanya kana kurwadziwa neuropathic.
3. Antibacterial uye antifungal basa

Pulegone ine inhibitory migumisiro pane zvakasiyana-siyana zveGram-positive uye Gram-negative mabhakitiriya, zvakadai seStaphylococcus aureus, Escherichia coli, Bacillus subtilis, nezvimwewo; inoratidzawo inhibitory kugona kurwisa fungi senge Candida albicans neAspergillus, uye inokodzera kugadzirwa kwezvichengetedzo zvechisikigo uye zvinomera-based anti-infective zvigadzirwa.
4. Mushonga unodzinga zvipembenene uye basa rekuuraya zvipembenene

Nekuda kweiyo inhibitory mhedzisiro pane twutsinga twetsinga, Pulegone inoshandiswa zvakanyanya mumasikirwo ezvipembenene zvinouraya zvipembenene, izvo zvinogona kunyatso dzinga umhutu, mite, nhunzi dzemichero, nezvimwewo, uye ine yakanaka kuenderana kwezvakatipoteredza uye biodegradability.
5. Inogona anti-bundu chiitiko (yekutanga tsvakurudzo)

Zvidzidzo zvekutanga zvakaratidza kuti Pulegone inogona kunge iine inhibitory mhedzisiro pane mamwe masero emudumbu (akadai sekenza yemazamu maseru) nekuita apoptosis, kudzora oxidative kusagadzikana uye mitochondrial basa, nezvimwewo, izvo zvinopa hwaro hwekutsvagisa kwechisikigo anti-cancer lead compounds.
Nzvimbo dzekushandisa uye zvinotarisirwa mhedzisiro
●Pharmaceutical industry

Sechisikigo chinotungamira mamorekuru mukuvandudza zvinodhaka, Pulegone inogona kushandiswa seyepakati kutora chikamu mukugadzirwa kwe menthol (Menthol), menthone, flavour additives uye inogona anti-kuzvimba uye antibacterial mishonga mitsva. Iine tarisiro yakafara yekushandiswa mukuvandudzwa kwemishonga yechinyakare yeChinese uye kugadzirira kwemishonga yechisikigo.
●Cosmetics uye makemikari ezuva nezuva

Nekunhuhwirira kwayo uye kuita kwemishonga inorwisa mabhakitiriya, Pulegone inoshandiswa kugadzirira zvekugezesa muromo, zvekugezesa muromo, mishonga yekugezesa, mite sprays, zvigadzirwa zvinodzinga umhutu, nezvimwewo, kusangana nemusika kudiwa kwegirinhi, kushomeka-kushatirwa, uye kuchengetedzwa kwakanyanya kwemazuva ese makemikari.
●Zvekurima uye zvekuchengetedza nharaunda zvinodzinga zvipembenene

Pulegone, sechisikigo chemishonga inouraya zvipembenene, inoshandiswa kugadzira mishonga yezvipembenene inodiwa pakurima organic, kuderedza kusvibiswa kwezvakatipoteredza, kuvandudza mhando yezvirimwa, uye kutevedzera hurongwa hwekusimudzira kurima.
Kuzvipira kwemhando yeGentolex Group

Iyo Pulegone API yakapihwa neGentolex Boka redu ine inotevera mhando vimbiso:

Kuchena kwepamusoro: kuchena ≥99%, yakakodzera kushandiswa kwemishonga uye yakakwirira-yekupedzisira maindasitiri

Inopindirana neGMP uye ISO mhando yekutonga system zvinodiwa

Ipa yakakwana yemhando yekuongorora mishumo (COA, inosanganisira GC/HPLC ongororo, simbi dzinorema, zvakasara zvinonyungudutsa, microbial miganhu)

Madimikira akaomeswa anogona kupihwa zvinoenderana nezvinodiwa nevatengi, kutsigira kupihwa kubva magiramu kusvika makirogiramu