Semaglutide yeRudzi 2 Chirwere cheshuga
Product Detail
| Zita | Semaglutide |
| CAS nhamba | 910463-68-2 |
| Molecular formula | C187H291N45O59 |
| Molecular uremu | 4113.57754 |
| Nhamba yeEINECS | 203-405-2 |
Mashoko anoreva zvakafanana
Sermaglutide;Semaglutide fandachem;Semaglutide tsvina;Sermaglutide USP/EP;semaglutide;Sermaglutide CAS 910463 68 2;Ozempic,
Tsanangudzo
Semaglutide chizvarwa chitsva cheGLP-1 (glucagon-like peptide-1) analogs, uye semaglutide inguva yakareba-yekuita dosage fomu yakagadziridzwa yakavakirwa pane yakakosha chimiro che liraglutide, ine mhedzisiro irinani mukurapa kwerudzi rwechipiri chirwere cheshuga.Novo Nordisk akapedza 6 Phase IIIa zvidzidzo zve semaglutide jekiseni, uye akatumira mushonga mutsva wekunyoresa zvinodhaka semaglutide vhiki nevhiki jekiseni kuUS Food and Drug Administration (FDA) musi waDecember 5, 2016. A Marketing Authorization Application (MAA) yakatumirwawo kune iyo European Medicines Agency (EMA).
Inofananidzwa ne liraglutide, semaglutide ine yakareba aliphatic chain uye yakawedzera hydrophobicity, asi semaglutide inogadziriswa neketani pfupi yePEG, uye hydrophilicity yayo inowedzerwa zvikuru.Mushure mekugadzirisa PEG, haigoni kungosunga padhuze nealbumin, kuvhara iyo enzymatic hydrolysis saiti yeDPP-4, asi zvakare kuderedza kubuda kwerenal, kurebesa hafu yehupenyu hwehupenyu, uye kuwana mhedzisiro yekutenderera kwenguva refu.
Application
Semaglutide inguva yakareba-yekuita dosage fomu yakagadziridzwa yakavakirwa pane yekutanga chimiro che liraglutide, iyo inoshanda zvakanyanya mukurapa rudzi rwechipiri chirwere cheshuga.
Bioactivity
Semaglutide (Rybelsus, Ozempic, NN9535, OG217SC, NNC0113-0217) inobata kwenguva refu glucagon-like peptide 1 (GLP-1) analog, agonist yeGLP-1receptor, ine angangoita mhando 2 Therapeutic efficacy ye2diabetes mellitus. )
Quality System
Kazhinji, hurongwa hwemhando uye vimbiso iri munzvimbo inovhara nhanho yese yekugadzirwa kwechigadzirwa chakapedzwa.Yakakwana kugadzira uye kutonga mashandiro anoitwa zvichiteerana nematanho akabvumidzwa / zvakatemwa.Shanduko yekudzora uye Kutsauka kwekubata system iripo, uye inodiwa ongororo yekuongorora uye kuferefeta kwakaitwa.Matanho akakodzera aripo ekuona kunaka kwechigadzirwa chisati chaburitswa mumusika.
