Ganirelix acetate peptide API

Tsananguro pfupi:

Zita: Ganirelix acetate

Cas nhamba: 123246-29-7

Molecular Formula: C80H113CLN11

Solley Huremu: 1570.34

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Chigadzirwa Chinhu

Zvigadzirwa tags

Chigadzirwa Chinhu

Zita	Ganirelix acetate
Nhamba	123246-29-7
Molecular Formula	C80H113CLN11
Sreek inoremerwa	1570.34

Synonyms

AC-DNAL-DCPA-DPA-SER-TYR-DHAR (ET2) -ELU-HAR (ET2 YEMAHARA -NH2; Ganirelix acetate; Ganirelix; Ganirelix acetate USP / EP /

Tsananguro

Ganirelix iri synthetic decapeid, uye yayo acetita munyu, Ganirelix acetate ndeye gonadotropin-kuburitsa hormone (GNRH) Receptor. Iyo AMINO ACID sequence is: AC-D-2NAL-D-3PPAL-D-Homoarg (9,10-et2) -Pro-Pro-D- Ala-NH2. Kunyanya kuungana, inoshandiswa muvakadzi vakabatsira tekinoroji yekuzvidzivirira kweOvari inomutsa zvirongwa zvekudzivirira kusarongeka kweHormone Peaks Peaks uye kubata zvisinganzwisisike nekuda kweichi chikonzero. Mushonga uyu une hunhu hwekuita kushoma kuita, hwakanyanya nhumbu mwero uye nguva pfupi yekurapa, uye ine zvakanakira kufananidzwa nemishonga yakafanana mukuita kwekiriniki.

Pharmacological chiito

Iyo pulsatile kuburitswa kweGonadotropin-kuburitsa hormone (GNRH) inomutsa iyo synthesis uye secretion ye lh naFs. Iyo frequency ye lh pulses pakati uye kunonoka kupfupika zvikamu zvinenge 1 paawa. Aya mapulses anoratidzwa mumasango anokwira muSerum LH. Panguva yepakati-yekuenda kumwedzi, kusunungurwa kukuru kweGNRH kunokonzera kuwanda kweLH. Iyo miyelmenstrual lh yekuvhiya inogona kukonzera mhinduro dzinoverengeka, kusanganisira: ovulation, oocyte oootic kutangazve, uye corpus luteum yekuumbwa. Kuumbwa kweiyo Corpus Luteum kunoita kuti Serum Progesterone mazinga kuti asimuke, nepo Estradiol mazinga anowira pasi. Ganirelix acetate ignrh antigonist iyo inokwikwidza inokwira maburi eGNRH Receptors pane pituitary gonadotrophs uye inotevera transduction nzira. Iyo inoburitsa nekukurumidza, kudzoreredza inhibition yeGonadotropin Secretion. Iyo inhibitory mhedzisiro yeGanirelix acetate pane Pituitary LH Secrodion yaive yakasimba pane iyo paFsS. Ganirelix acetate yakatadza kunyengedza kuburitswa kwekutanga kweEndoenayo Gonadotropins, zvinoenderana neAntagonism. Kupedzisa kwakazara kwePituitary LH uye FHS Levels yakaitika mukati memaawa makumi mana nemasere mushure mekunge Ganirelix acetate yakadzimwa.

Yapfuura: Cetrerelix acetate kuti idzivise preemature Ovulation 120287-85-6

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