Terlinksin acetate ye Esophageal Vilceal Bhuroka
Chigadzirwa Chinhu
| Zita | N- (n- (n-gulycylglycycyl) glycyl) -8-l-lysinevasopressin |
| Nhamba | 14636-16-5 |
| Molecular Formula | C52H74n15o15s2 |
| Sreek inoremerwa | 1227.37 |
| Einecs nhamba | 238-680-8 |
| Boiling Point | 1824.0 × 65.0 ° C (yakafanotaura) |
| Density | 1.46 ± 0.1 g / cm3 (yakafanotaura) |
| Mamiriro ekuchengetedza | Rambai munzvimbo ine rima, inert mamiriro enzvimbo, chengetedza mu freezer, pasi pe -15 ° C. |
| Acidity coefficient | (pka) 9.90 ± 0.15 (akafanotaura) |
Synonyms
[N-n-α-triglycycyl-8-lysine] -vasopressin; 1-Triglycyl-8-lysinevasopressin; MaNay-GLYCL-GLYCL- [8-LYSINE] -Vasopressin; MaNay-GLYCL-GLYCL-LYSINE-Vasopressin; Nay-glycylglycylglycycycycyl-Vasopressin; Ma-egly-gly-gly-8-lys-vasopressin; Terlinessin, terlinrsine, terlinessina, terlinressinum.
Tsananguro
Terlinessin, ane zita remakemikari ane zita rekiritylsine Vasopressin, itsva nyowani yekugadzira-scinksin gadziriro yekugadzirira. Ndiwo rudzi rwechiratidzo, rwusina basa roga. Inoitwa naAminopeptidase muVivo Kuti Vivwe zvishoma nezvishoma "kusunungurwa" Anoshanda Lysine Vasopressin mushure mekubvisa matatu GLYCLES ART N-Terminus. Naizvozvo, terlinressin inoita sechiteshi chinoburitsa lysine Vasopressin pachiyero chakatsiga.
Iyo pharmacological mhedzisiro yematauro ndeyekukomberedza splanchnic vasculy muswe uye kuderedza kuyerera kweropa (spleen, utercus, uye nekudaro kuderedza kuyerera kweropa kuyerera kweropa uye nekudzora portal. Kune rimwe divi, zvinogona kudzikisawo plasma mhedzisiro yeRenin kuyerera, nekukasira kuyerera kweropa, nekuvandudza renal basa uye kuwedzera kubuda mune varwere vane chirwere cheHepatorenal syndrome. Terlinress parizvino iri chete zvinodhaka izvo zvinogona kuvandudza huwandu hwevarwere neEsophageal viceial hemorrhage. Yakanga inonyanya kushandiswa mukurapa kwekiriniki yeiceal hemorrhage. Mukuwedzera, terlinressin yakashandiswa zvakare kushandiswa muchiropa neitsvo. Kazhinji, zvinoita kuti iite basa rinobatsira mukusagadzikana kwekunyepedzera kuvhunduka uye kukazve Cardiopulmonary kudzokorora. Kuenzaniswa neVasopressin, ine simba refu, hazvipindire matambudziko ane zvakawanda, kusanganisira matambudziko akanyanya muhurongwa hwemwoyo, uye zviri nyore kushandisa (intravenous jekiseni), iyo yakakwaniswa kuti ive hanya nekuchenjera uye kutarisirwa kwakasimba. Kununura uye kurapwa kwevarwere vanorwara zvakanyanya.
